Colorectal Cancer: A Comprehensive Guide

About Colorectal Cancer

Colorectal cancer (CRC), a prevalent and potentially fatal disease, manifests predominantly as large bowel cancer, with an annual diagnosis of approximately 145,600 new cases in the United States. It stands as a leading cause of cancer-related deaths, particularly among men.

Symptoms and Signs

Individuals with CRC may experience a range of symptoms including:

  • Change in Bowel Habits: The most prevalent symptom, observed in 74% of cases.
  • Rectal Bleeding: Often accompanied by a change in bowel habits, noted in 51% of all cases and 71% of cases with rectal bleeding.
  • Rectal or Abdominal Mass: Detected in 24.5% and 12.5% of cases respectively.
  • Iron Deficiency Anemia: Present in 9.6% of cases.
  • Abdominal Pain: The least common symptom, occurring in 3.8% of cases.


The diagnosis of CRC is primarily established through histologic examination of biopsy samples, typically obtained during lower gastrointestinal tract endoscopy or from a surgical specimen. The majority of CRC cases are adenocarcinomas. Diagnostic procedures may include colonoscopy or CT colonography, particularly when symptoms or signs suggestive of CRC are present. The multidisciplinary team involved in CRC care generally encompasses a surgeon, medical oncologist, radiation oncologist, and a gastroenterologist.

Conventional Treatment

Conventional treatment strategies for CRC include colostomy, chemotherapy, and radiation therapy, often implemented in a combined approach to enhance treatment efficacy.

Integrative Treatments for Colorectal Cancer

In addition to conventional treatments, integrating complementary therapies can potentially enhance the treatment efficacy. Here are some integrative treatments justified for use in colorectal cancer patients:

  • Autologous Immunotherapy: Utilizes the patient’s immune cells to target and eliminate cancer cells, enhancing the body’s natural defense mechanisms.
  • Pharmacological Immunotherapy: Involves the use of drugs to boost the immune system’s ability to fight cancer cells, offering a targeted approach to cancer treatment.
  • Systemic Perfusion Hyperthermia: A treatment method that uses heat to increase the vulnerability of cancer cells to other treatments, enhancing the effectiveness of primary therapies.
  • Systemic Ozone Therapy: This therapy involves introducing ozone gas into the body to improve oxygenation and potentially inhibit cancer cell growth.
  • Glutathione: A powerful antioxidant that helps protect cells from damage, playing a protective role in cancer treatment.
  • Dendritic Enhancers: These are used to boost the immune response by enhancing the function of dendritic cells, which play a crucial role in immune responses.
  • Mistletoe: Used as a complementary therapy, mistletoe can help improve symptoms and enhance the quality of life in cancer patients.
  • Personalized Nutrition: Tailoring nutrition plans to the individual needs of the patient, supporting overall health and well-being during cancer treatment.
  • Vitamin D IV: Administered intravenously, it helps in enhancing the immune response and may have protective effects against cancer.
  • Zinc: An essential mineral that plays a role in immune function and may help in improving the response to cancer treatment.
  • Melatonin: A hormone that can help in managing sleep disturbances in cancer patients, enhancing the quality of life.
  • Curcumin: A compound found in turmeric, it has anti-inflammatory and antioxidant properties, potentially offering protective effects against cancer.
  • Sylimarin: A compound found in milk thistle, it has antioxidant properties and may help in protecting liver function during cancer treatment.
  • Vitamin E: A potent antioxidant that helps in protecting cells from damage, supporting overall health during cancer treatment.

By incorporating these integrative treatments, patients can experience a more holistic approach to cancer care, potentially enhancing the effectiveness of conventional treatments and improving the quality of life

Conventional Treatment


Sometimes, a person with rectal cancer may need to have a colostomy. This is a surgical opening, or stoma, through which the colon is connected to the abdominal surface to provide a pathway for waste to exit the body. This waste is collected in a pouch worn by the patient. Sometimes, the colostomy is only temporary to allow the rectum to heal, but it may be permanent.


For rectal cancer, radiation therapy may be used before surgery, called neoadjuvant therapy, to shrink the tumor so that it is easier to remove. It may also be used after surgery to destroy any remaining cancer cells, chemotherapy is often given at the same time as radiation therapy, called chemoradiation therapy, to increase the effectiveness of the radiation therapy.

Systemic Therapy

Systemic therapy is the use of medication to destroy cancer cells. This type of medication is given through the bloodstream to reach cancer cells throughout the body. Systemic therapies are generally prescribed by a medical oncologist common way to give systemic therapies include an intravenous (IV) tube placed into a vein using a needle or in a pill or capsule that is swallowed (orally).

The types of systemic therapies used for colorectal cancer include:

  • Chemotherapy
  • Targeted therapy

Alternative medicine for Colon Cancer

Immunotherapy / Cellular therapy

As populations of useful bacteria decline over time, bowel-specific immunity and general immune system function deteriorate. The immune system’s overall ability to fight infection and cancer wanes, while inappropriate immune responses, including excessive inflammation, increase. CT can both boost appropriate infection- and cancer-fighting immune functions, and also help to suppress the inflammatory response when it gets out of control.

Autologous cancer vaccines have been studied extensively, with the most encouraging results noted in randomized, controlled clinical trials including more than 1,300 colorectal cancer patients in which tumor vaccines were given after surgery. These trials reported reduced recurrence rates and improved survival.


Hyperthermia involves the use of heat to directly treat a tumor or increase the vulnerability of cancer cells to other forms of treatment, such as immunotherapy, vitamin C, chemotherapy or radiotherapy.

On one study colon adenocarcinoma cells demonstrated a promising decrease in cell viability after treatment with the low dose chemotherapy and heat.
Another study confirmed a potent anti-tumor efficacy caused combined thermo-chemotherapy.

Ozone/ Oxygen therapies

Ozone therapy is an effective medical treatment for different diseases like mucositis, psoriasis, acute pain, neurovascular diseases, and cancer.

Studies have shown that ozone could be useful in colon cancer management in combination with nutraceuticals or LDQT w/ 5-fluorouracil and cisplatin with significant inhibition of cytokines having a central role in colon cancer cell survival and chemoresistance.

Complimentary medicine used for associated conditions of colon cancer

B Complex

Comprehensive studies have linked a high intake of dietary or supplemental Folate and high blood Folate levels with a reduced risk of colon cancer. Folate and vitamin B12 deficiency is associated with depletion of the major intracellular antioxidant glutathione, and oxidative stress is emerging as an etiological mechanism for colon cancer.

Folate and vitamin B12 supplementation decreased the level of oxidative stress and ameliorated the cytotoxic effects of chemotherapy. Also Folate and vitamin B12 supplementation combats carcinogen-induced oxidative stress.


An essential trace mineral, selenium is one of the most important cancer-fighting nutrients. Scientists have noted a statistically significant correlation between low soil concentrations of selenium and increased rates of colorectal cancer.

Selenium supplementation at the time of cancer surgery can increase local immune function, an effect that may reduce recurrence. There may also be synergistic effects of selenium with other nutrients such as Folate.

A clinical trial of 200 mcg of selenium versus placebo found that the incidence of colorectal cancer was significantly less in those taking selenium.


Curcumin is a powerful anti-inflammatory compound that acts on NF-kB, a proinflammatory mediator that influences hundreds of genes involved in the growth and spread of cancer. In addition, Curcumin regulates tumor suppressor pathways and triggers mitochondrial-mediated death in cancer cells.

It also helps to starve tumors of their vital blood supply and it can oppose many of the processes that permit metastases to spread.

Omega 3 fatty acids

O3FA work in different pathways to combat and prevent colon cancer. Multiples studies show that the populations with a higher intake have a lower risk of developing colon cancer.

O3FA reduce the pro-tumor effects of many molecules involved in the growth and spread of colon cancer, including vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), platelet-derived endothelial cell growth factor (PDECGF), cyclo-oxygenase 2 (COX-2), prostaglandin-E2 (PGE2), nitric oxide, NF-kB, matrix metalloproteinases and beta-catenin
Experiments have shown EPA and DHA can make cancer cells more vulnerable to damage from nutraceuticals, immunotherapy, chemotherapy and radiation, thus encouraging the cells to turn on cell death pathways in lieu of repair pathways.

Diseases Treated at Integrative Immunotherapy Institute

Adrenal Cancer
Anal Cancer
Appendix Cancer
Bile Duct Cancer
Bladder Cancer
Bone Cancer
Brain Cancer
Breast Cancer
Carcinoid Tumors
Cervical Cancer
Colorectal Cancer
Esophageal Cancer
Eye Cancer
Gallbladder Cancer
Gastrointestinal Stromal Tumors (GIST)
Head and Neck Cancer
Hodgkin Lymphoma
Intestinal Cancer

Kidney Cancer
Liver Cancer
Lung Cancer
Metastatic Squamous Neck Cancer
Multiple Myeloma
Non-Hodgkin Lymphoma (NHL)
Oral Cancer
Ovarian Cancer
Pancreatic Cancer
Penile Cancer
Primary Central Nervous System (CNS) Lymphoma
Prostate Cancer
Sinus Cancer
Skin Cancer

Small Intestine Cancer
Soft Tissue Sarcoma
Spinal Cancer
Squamous Cell Carcinoma
Stomach Cancer
Testicular Cancer
Throat Cancer
Thymoma / Thymic Carcinoma
Thyroid Cancer
Urethral Cancer
Uterine Cancer
Vaginal Cancer
Vulvar Cancer

Bacterial & Viral Infections
Hepatitis C
Lyme Disease

Addison’s Disease
Autoimmune Inner Ear Disease (AIED)
Celiac Disease

Crohn’s Disease Treatment in Mexico – Top Clinic
Cushing Syndrome
Graves’ Disease
Guillain-Barre Syndrome

Hemolytic Anemia

Alzheimer’s Disease
Hypertension (High Blood Pressure)
Parkinson’s Disease