Melanoma: A Comprehensive Overview

About Melanoma

Melanoma, a severe form of skin cancer, arises when skin cells undergo abnormal transformations and proliferate uncontrollably. This type of cancer can manifest anywhere on the skin, including areas that are not easily visible. It originates from melanocytes, the cells responsible for skin pigmentation. Melanoma is witnessing a rapid increase in incidence, making it the sixth most common cancer in the United States. If not addressed timely, it can metastasize to various organs within the body, making treatment more complex.


The diagnosis of melanoma involves determining the stage of the cancer, which is based on the tumor’s thickness, its spread, and aggressiveness. This staging is vital in devising an effective treatment plan.

Conventional Treatments

Melanoma treatment generally involves one or more of the following strategies:

  • Surgery: Primarily involves the removal of the cancerous growth, often accompanied by an examination of nearby lymph nodes to assess the extent of the spread.
  • Radiation Therapy: Utilized to eradicate cancer cells.
  • Immunotherapy: Employs drugs to stimulate the immune system to target and eliminate cancer cells.
  • Targeted Therapy: Involves the use of drugs that inhibit specific enzymes or molecules crucial to the growth of cancer cells.
  • Chemotherapy: Utilizes drugs that hinder the growth of cancer cells by interfering with their ability to divide or reproduce.

Integrative Medicine for Melanoma

In addition to conventional treatments, the following integrative therapies can be considered to potentially enhance the effectiveness of the primary treatment plan:

  • Autologous Immunotherapy: This therapy uses the patient’s immune cells to target and eliminate cancer cells, potentially enhancing the body’s natural defense mechanisms against melanoma.
  • Pharmacological Immunotherapy: Involves the use of drugs to boost the immune system’s ability to fight melanoma cells, offering a targeted approach to cancer treatment.
  • Dendritic Enhancers: These are used to boost the immune response by enhancing the function of dendritic cells, which play a crucial role in immune responses against cancer cells.
  • Systemic Perfusion Hyperthermia: This treatment method uses heat to increase the vulnerability of melanoma cells to other treatments, potentially enhancing the effectiveness of primary therapies.
  • Mistletoe: Utilized as a complementary therapy, mistletoe can help improve symptoms and enhance the quality of life in melanoma patients.
  • Glutathione: A powerful antioxidant that helps protect cells from damage, potentially playing a protective role in melanoma treatment.
  • Personalized Nutrition: Involves tailoring nutrition plans to the individual needs of the patient, supporting overall health and well-being during melanoma treatment.
  • Vitamin D IV: Administered intravenously, it helps in enhancing the immune response and may have protective effects against melanoma.
  • Zinc: An essential mineral that plays a role in immune function and may help in improving the response to melanoma treatment.
  • Melatonin: A hormone that can help in managing sleep disturbances in melanoma patients, enhancing the quality of life.
  • Curcumin: A compound found in turmeric, it has anti-inflammatory and antioxidant properties, potentially offering protective effects against melanoma.
  • Sylimarin: A compound found in milk thistle, it has antioxidant properties and may help in protecting liver function during melanoma treatment.
  • Vitamin E: A potent antioxidant that helps in protecting cells from damage, supporting overall health during melanoma treatment.

By incorporating these integrative treatments, melanoma patients can potentially benefit from a more holistic approach to cancer care, which may enhance the effectiveness of conventional treatments and improve the quality of life.


The goal of cancer immunotherapy is to improve the body’s natural ability to find and destroy cancer cells. Successful immunotherapeutic approaches stimulate the natural defenses of the immune system and provide new ways to attack cancer. This is possible with comprehensive interventions that include cell therapy / immuno-pharmacological therapy in combination with nutritional, endocrine measures and supplements.

Dendritic enhancer or T-cell modulators

T-cell Modulators are peptide chains composed of tens of amino acids that appear to store all the experience of the immune system. The great intellectual leap to understand is that T-cell Modulators do not transfer antibodies nor create them directly, but its function is to educate, and teach the immune cells to recognize specific antigens that could happen to them unnoticed.

T-cell Modulators do not cure anything but work to make a “smarter” immune system so that it is the body itself eliminating disease. They are therefore vital in developing the strategies of the immune system against cancer.

T-cell Modulators contains several immunoactivity components that have been shown to act synergistically in raising Dendritic and NK function and effective as adjuvant therapy in soft tissue sarcoma, elevating dendritic and NK function as much as 250%


Hyperthermia involves the use of heat to directly treat a tumor or increase the vulnerability of cancer cells to other forms of treatment, such as immunotherapy, B17, vitamin C, chemotherapy or radiotherapy.

Liposomal Mistletoe

Mistletoe helps fight tumor-induced immune suppression. Natural killer cells (NK) are a type of white blood cell that looks for and destroys Prostate cancer cells. Research has shown that NK cells can spontaneously recognize and kill a variety of cancer cells.

Mistletoe has been called a biological response modifier due to its ability to improve various aspects of immune function. Studies show that it activates natural killer cells, T cells, macrophages and monocytes.

A special proprietary form of liposomal mistletoe created with nanotechnology has been created for use in our Prostate cancer treatment approach.


Glutathione is the most important antioxidant produced by your body and a master detoxifier of every cell in your body. It prevents cellular damage caused by free radicals and peroxides. Glutathione metabolism can play both protective and pathogenic roles. It is crucial in the removal and detoxification of carcinogens, and alterations in this pathway can have a profound effect on cell survival. However, by conferring resistance to several chemotherapeutic drugs, elevated levels of glutathione in tumor cells can protect such cells.

Vitamin D

Vitamin D is a fat-soluble micronutrient, which plays a role in the maintenance of calcium and phosphate homeostasis, predominantly increasing the gut absorption of calcium and phosphate. High concentrations of circulating vitamin D has been found to be associated with reduced melanoma progression and improved survival. Furthermore, reduced vitamin D serum levels have been reported in patients with stage IV melanoma compared with those with stage I.

A study done to 204 patients suggests a role of vitamin D levels in melanoma aggressiveness and raises the question as to whether vitamin D levels should be monitored, or even supplemented, in people with low yearly sun exposure.


Healthy prostate cells accumulate zinc to accomplish their normal cellular functions. In contrast, prostate cancer cells have depleted zinc stores, which makes them less susceptible to cell death.


Melatonin, a hormone best known for its role in regulating sleep, is also emerging as a promising anti-cancer agent. Evidence to date has shown that melatonin can interfere with cancer initiation, progression, and metastasis.

Studies indicates an oncostatic capacity of melatonin in time-dependent manner (24, 48, 72 hours) in highly pigmented MNT-1 melanoma cells.

Fish Oil and Omega-3 Fatty Acid

These fatty acids have many health benefits and may even slow the growth of melanoma. In laboratory and animal studies, omega-3 fatty acids were found to inhibit inflammation, interfere with blood vessel growth in tumors, and cause cancer cells to die.

The treatment by gavage with a mixture of fish and soybean oils (1:1 ratio) both reduced the melanoma growth and the levels of leukotriene B4 (LTB4), prostaglandin E2 (PGE2), PGE2/prostaglandin E3 (PGE3) ratio, and CXC ligand 1 (CXCL1) and increased the levels of interleukin 10 (IL-10) to IL-10/CXCL1 ratio in the melanoma microenvironment.

Diseases Treated at Integrative Immunotherapy Institute

Adrenal Cancer
Anal Cancer
Appendix Cancer
Bile Duct Cancer
Bladder Cancer
Bone Cancer
Brain Cancer
Breast Cancer
Carcinoid Tumors
Cervical Cancer
Colorectal Cancer
Esophageal Cancer
Eye Cancer
Gallbladder Cancer
Gastrointestinal Stromal Tumors (GIST)
Head and Neck Cancer
Hodgkin Lymphoma
Intestinal Cancer

Kidney Cancer
Liver Cancer
Lung Cancer
Metastatic Squamous Neck Cancer
Multiple Myeloma
Non-Hodgkin Lymphoma (NHL)
Oral Cancer
Ovarian Cancer
Pancreatic Cancer
Penile Cancer
Primary Central Nervous System (CNS) Lymphoma
Prostate Cancer
Sinus Cancer
Skin Cancer

Small Intestine Cancer
Soft Tissue Sarcoma
Spinal Cancer
Squamous Cell Carcinoma
Stomach Cancer
Testicular Cancer
Throat Cancer
Thymoma / Thymic Carcinoma
Thyroid Cancer
Urethral Cancer
Uterine Cancer
Vaginal Cancer
Vulvar Cancer

Bacterial & Viral Infections
Hepatitis C
Lyme Disease

Addison’s Disease
Autoimmune Inner Ear Disease (AIED)
Celiac Disease

Crohn’s Disease Treatment in Mexico – Top Clinic
Cushing Syndrome
Graves’ Disease
Guillain-Barre Syndrome

Hemolytic Anemia

Alzheimer’s Disease
Hypertension (High Blood Pressure)
Parkinson’s Disease