About Melanoma

Melanoma is a serious form of skin cancer. It happens when normal cells in the skin change into abnormal cells and grow out of control.

Melanoma can occur anywhere on the skin, including the back and other hard-to-see areas. It can also occur on the skin lining the mouth, nose, and genitals. When it is not treated, melanoma can spread to organs inside the body. Melanoma can run in families.

Melanoma is a form of cancer that develops in the cells (melanocytes) that make our skin color. Melanoma is the sixth most common cancer in the United States, and the number of melanoma cases diagnosed annually is increasing faster than for any other cancer.

Melanoma generally starts as a single tumor or lesion. Cancer cells can then spread to nearby lymph nodes and/or distant sites throughout the body. Once melanoma spreads to distant locations, it is called advanced or metastatic. Rarely, melanoma is diagnosed when a person presents with distant metastases, and no primary site on the skin or elsewhere can be found.


After melanoma is diagnosed, the next step is to determine the cancer’s stage, which is based upon the thickness of the tumor, the extent of its spread, and its aggressiveness. Staging is important to determine the most appropriate treatment.

Conventional treatments

Most people with melanoma have one or more of the following treatments depending on the stage:

  • Surgery – Melanoma is usually treated with surgery to remove the cancer. That’s usually true even if the biopsy appeared to have removed the whole abnormal area. During surgery, the doctor might also check nearby lymph nodes to see if the melanoma has spread inside the body. Lymph nodes are bean-shaped organs under the skin that store infection-fighting cells.
  • Radiation therapy – Radiation can kill cancer cells.

There are three main categories of drug treatments (systemic treatments):

  • Immunotherapy – Drugs that stimulate or unleash the immune system to attack and kill the cancer cells. Several different types of immunotherapy have been developed, the most important of which are checkpoint inhibitors nivolumab [brand name: Opdivo], pembrolizumab [brand name: Keytruda], ipilimumab [brand name: Yervoy]), which have largely replaced high-dose interleukin-2 (IL-2). Significant progress has been made in the treatment of patients with metastatic melanoma over the past decade. The anti-programmed cell death 1 (PD-1) checkpoint inhibitors (nivolumab, pembrolizumab) and the combination of nivolumab plus ipilimumab are effective for controlling metastatic melanoma and prolonging life in nearly half of all patients. However, immunotherapy (nivolumab, pembrolizumab, ipilimumab) can be associated with severe side effects. Fortunately, these can usually be controlled with a brief course of immunosuppressive drugs without interfering with the control of the tumor in most cases.
  • Targeted therapy – Drugs that inhibit specific enzymes or molecules important to the cancer cells.
  • Chemotherapy – Drugs that stop or slow the growth of cancer cells by interfering with their ability to divide or reproduce themselves.

Integrative medicine For Melanoma


The goal of cancer immunotherapy is to improve the body’s natural ability to find and destroy cancer cells. Successful immunotherapeutic approaches stimulate the natural defenses of the immune system and provide new ways to attack cancer. This is possible with comprehensive interventions that include cell therapy / immuno-pharmacological therapy in combination with nutritional, endocrine measures and supplements.

Dendritic enhancer or T-cell modulators

T-cell Modulators are peptide chains composed of tens of amino acids that appear to store all the experience of the immune system. The great intellectual leap to understand is that T-cell Modulators do not transfer antibodies nor create them directly, but its function is to educate, and teach the immune cells to recognize specific antigens that could happen to them unnoticed.

T-cell Modulators do not cure anything but work to make a “smarter” immune system so that it is the body itself eliminating disease. They are therefore vital in developing the strategies of the immune system against cancer.

T-cell Modulators contains several immunoactivity components that have been shown to act synergistically in raising Dendritic and NK function and effective as adjuvant therapy in soft tissue sarcoma, elevating dendritic and NK function as much as 250%


Hyperthermia involves the use of heat to directly treat a tumor or increase the vulnerability of cancer cells to other forms of treatment, such as immunotherapy, B17, vitamin C, chemotherapy or radiotherapy.

Liposomal Mistletoe

Mistletoe helps fight tumor-induced immune suppression. Natural killer cells (NK) are a type of white blood cell that looks for and destroys Prostate cancer cells. Research has shown that NK cells can spontaneously recognize and kill a variety of cancer cells.

Mistletoe has been called a biological response modifier due to its ability to improve various aspects of immune function. Studies show that it activates natural killer cells, T cells, macrophages and monocytes.

A special proprietary form of liposomal mistletoe created with nanotechnology has been created for use in our Prostate cancer treatment approach.


Glutathione is the most important antioxidant produced by your body and a master detoxifier of every cell in your body. It prevents cellular damage caused by free radicals and peroxides. Glutathione metabolism can play both protective and pathogenic roles. It is crucial in the removal and detoxification of carcinogens, and alterations in this pathway can have a profound effect on cell survival. However, by conferring resistance to several chemotherapeutic drugs, elevated levels of glutathione in tumor cells can protect such cells.

Vitamin D

Vitamin D is a fat-soluble micronutrient, which plays a role in the maintenance of calcium and phosphate homeostasis, predominantly increasing the gut absorption of calcium and phosphate. High concentrations of circulating vitamin D has been found to be associated with reduced melanoma progression and improved survival. Furthermore, reduced vitamin D serum levels have been reported in patients with stage IV melanoma compared with those with stage I.

A study done to 204 patients suggests a role of vitamin D levels in melanoma aggressiveness and raises the question as to whether vitamin D levels should be monitored, or even supplemented, in people with low yearly sun exposure.


Healthy prostate cells accumulate zinc to accomplish their normal cellular functions. In contrast, prostate cancer cells have depleted zinc stores, which makes them less susceptible to cell death.


Melatonin, a hormone best known for its role in regulating sleep, is also emerging as a promising anti-cancer agent. Evidence to date has shown that melatonin can interfere with cancer initiation, progression, and metastasis.

Studies indicates an oncostatic capacity of melatonin in time-dependent manner (24, 48, 72 hours) in highly pigmented MNT-1 melanoma cells.

Fish Oil and Omega-3 Fatty Acid

These fatty acids have many health benefits and may even slow the growth of melanoma. In laboratory and animal studies, omega-3 fatty acids were found to inhibit inflammation, interfere with blood vessel growth in tumors, and cause cancer cells to die.

The treatment by gavage with a mixture of fish and soybean oils (1:1 ratio) both reduced the melanoma growth and the levels of leukotriene B4 (LTB4), prostaglandin E2 (PGE2), PGE2/prostaglandin E3 (PGE3) ratio, and CXC ligand 1 (CXCL1) and increased the levels of interleukin 10 (IL-10) to IL-10/CXCL1 ratio in the melanoma microenvironment.

Diseases Treated at Integrative Immunotherapy Institute

Adrenal Cancer
Anal Cancer
Appendix Cancer
Bile Duct Cancer
Bladder Cancer
Bone Cancer
Brain Cancer
Breast Cancer
Carcinoid Tumors
Cervical Cancer
Colorectal Cancer
Esophageal Cancer
Eye Cancer
Gallbladder Cancer
Gastrointestinal Stromal Tumors (GIST)
Head and Neck Cancer
Hodgkin Lymphoma
Intestinal Cancer

Kidney Cancer
Liver Cancer
Lung Cancer
Metastatic Squamous Neck Cancer
Multiple Myeloma
Non-Hodgkin Lymphoma (NHL)
Oral Cancer
Ovarian Cancer
Pancreatic Cancer
Penile Cancer
Primary Central Nervous System (CNS) Lymphoma
Prostate Cancer
Sinus Cancer
Skin Cancer

Small Intestine Cancer
Soft Tissue Sarcoma
Spinal Cancer
Squamous Cell Carcinoma
Stomach Cancer
Testicular Cancer
Throat Cancer
Thymoma / Thymic Carcinoma
Thyroid Cancer
Urethral Cancer
Uterine Cancer
Vaginal Cancer
Vulvar Cancer

Bacterial & Viral Infections
Hepatitis C
Lyme Disease

Addison’s Disease
Autoimmune Inner Ear Disease (AIED)
Celiac Disease

Crohn’s Disease Treatment in Mexico – Top Clinic
Cushing Syndrome
Graves’ Disease
Guillain-Barre Syndrome

Hemolytic Anemia

Alzheimer’s Disease
Hypertension (High Blood Pressure)
Parkinson’s Disease