What is Cryoblation?

Cryoblation is a minimally invasive treatment using extreme cold to kill cancer cells by freezing and destroying the diseased tissues. Also called cryosurgery, cryoablation, percutaneous cryotherapy or targeted cryoablation therapy.

How can it be used?

Cryotherapy is used to treat tumors in different parts of the body, such as the kidneys, bones (including the spine), lungs, and breasts (including benign breast lumps called fibroadenomas).

One hypotheses of how cryoablation induces an immune response is the way cell death is induced. Cryoablation induces cell death by both necrosis and apoptosis. Necrosis releases intra-cellular contents stimulating signals (among others danger signals) that may activate T cells for a specific immune response to the cryoablated tissue.


During cryoablation, a thin, wandlike needle (cryoprobe) is inserted into your skin and directly into the cancerous tumor. Next a gas is pumped into the cryoprobe freezing the diseased tissues. The gas is a liquid nitrogen or high pressure argon gas that flows through the cryoprobe. Physicians use image-guidance techniques such as ultrasound, computed tomography (CT) or magnetic resonance (MR) to help guide the cryoprobes to treatment sites located inside the body.


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Intraperitoneal Perfusion Hyperthermia
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Radiofrequency ablation (RFA)
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Specific Transfer Factor
T Cell Modulator Therapy
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